L’acetyl hexapeptide-3 is a synthetic cosmetic ingredient intended anti-wrinkle. In fact, it is a peptide, a fragment of SNAP-25a substrate of the botulinum toxin. L’acetyl hexapeptide-8 is marketed under the name Argireline by the research laboratory Lipotec, based in Barcelona.
How does botox work?
Botox is a drug that doctors have used for years for wrinkle treatment. Botox is the brand name for a toxin made by bacteria Clostridium botulinum. The term Botox is the one you hear most often because it was the first injectable botulinum toxin.
Its mode of action is as follows: It blocks the signals from the nerves to the muscles. As a result, the injected muscle is no longer able to contract. Therefore, this allows wrinkles to relax and fade.
Botox is most often used to treat forehead wrinkles and crow’s feet. However, it is of no use for sagging skin or wrinkles caused by overexposure to ultraviolet rays.
How long does the effect of Botox last?
The effect of Botox gradually dissipates after three to six months, depending on the person. As muscle action returns, fine lines and wrinkles begin to reappear and need to be addressed again.
How does Argireline work?
Argireline is a peptide able to to stare the water inside the epidermis and to support the protective function skin. Argireline is considered a neurotransmitter inhibitor peptide. In fact, this means that it could have an action on expression lines.
Studies on the use of a cream containing a concentration of 10% argireline have shown that this does not penetrate beyond the upper layers of the skin. And even after several hours. In effect, this means that argireline does not impact the factors in the underlying layers that lead to the formation of expression lines.
On the other hand, research has shown that this peptide can penetrate more into the skin if specific formula steps are followed, including the type of emulsion (higher water content has shown greater penetration).
Its benefits for the skin:
- Prevents the formation of expression lines : In short, it prevents the nerves from talking to the muscles and telling them to contract
- Boosts the production of collagen : Thus allowing to increase the level of hydration of the skin, to plump and play on the elasticity of the epidermis
- Helps retain moisture inside the skin : Skin hydration levels are optimized. Effect plump skinguaranteed!
Is argireline safe?
Nowadays, there are no known side effects of Argireline. Like many peptides, Argireline does not penetrate deep into the skin. Indeed, it is a large and complex molecule. Since it is not absorbed through the skin, it is unlikely to cause an allergic reaction. Nevertheless, we recommend that you perform a test on a small area of skin, such as the fold of your elbow, to avoid any unpleasant surprises when using the product on your face.
Does argireline work as well as Botox?
Argireline is as effective as botox in stopping the release ofacetylcholine (Chemical substance that is part of the neurotransmitters, ie secreted by certain neurons to transmit nerve impulses to other cells). Second, it allows reduce the depth of wrinkles, up to 30%.
In addition, argireline allowsimprove the skin’s hydration level. In fact, research shows that it improves the appearance of resting wrinkles.
However, this is not at all the mode of action of Botox: Effectively, botox acts by preventing the contraction of the muscles responsible for expression lines. Argireline cannot penetrate as deeply into the skin as botox, so it does not offer the same results as botulinum toxin.
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